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So maybe I could just replace what's one their mugshots, So instead of them going after viruses maybe they could go after a gene that causes Huntington Disease or Hemophilia.For example and this is actually something that's been done. And in a lot of them CRISPR made the wrong cuts and screwed up the cells.And that led them to conclude that this is a technology that's not ready right now for application in the human genome line. And I can just program it and it cuts DNA wherever I want. Getting rid of weak muscles and going for stronger ones, and on and on, and on. In 2012, scientists had a realization: hidden inside one of the world's smallest organisms, was one of the world's most powerful tools. I got to talk to Carl.So I, uh, I basically asked like “Why all the fuss?”, maybe it was just the alcohol, or but maybe there's something really happening here.Oh, there's something totally happening here. Um-They tried using CRISPR on about 86 embryos and they only got it to work right in maybe 28. We called up Carl again.Well we, we have to revisit, we have to revisit because in our Armageddon conversation in which I believe I was extremely alarmist and you were extremely down putting.I feel that I should do a small little parade of the-(laughs). About 60,000 kids are born a year through IVF, and it's probable that some of those parents chose whether they wanted a boy or a girl.And, and when people started doing IVF there was a huge controversy. Prominent scientists hope to stop further attempts at germline editing, at least for now.

Not yet but I think the dike has been opened. "Or would you like your child, to, to face, a, a, a future of, of Alzheimer. Jad Abumrad: They tried using CRISPR on about 86 embryos and they only got it to work right in maybe 28. Right.It turns out actually according to Jennifer Doudna that, that's actually not as hard as you would think.Yeah, apparently what you do is just throw this new good gene, kind of in the neighborhood of where the old gene used to be. It hasn't been built yet.It maybe 20 years from now but that's what you're looking at.

I don't see people who are unable to sleep at night because of the existence of IVF.You know now I'm going to sound like I'm on Robert's side of this.

And, um, I, I agree. It seems at the moment that you can take these things out of bacteria, stick them into almost any other creature and it still works.Do it corn, do it in anything. And I don't know where the designing stops.We sort of got into all of this with, uh, Carl Zimmer, science writer.If, if you can be very, very gene specific and you learn more and more about genes over time.

And if you imagine making these changes and they cascade through generation after generation.You could affect the evolution of organisms. Well one of lines that had been drawn but Jennifer Doudna and others was that we should not use this technology on humans who haven't been born yet.

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