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Children from a parent with heterozygous FVL mutation have a 25% chance of having inherited it from the parent who has the mutation.In the U.S., FVL is present in approximately 5% of the general population.
Advertising on our site helps support our mission. 1-ranked heart program in the United States.Cleveland Clinic Cancer Center provides world-class care to patients with cancer and is at the forefront of new and emerging clinical, translational and basic cancer research.Cleveland Clinic Community Care puts patients first by offering comprehensive, coordinated, personalized healthcare. Factor V Leiden is the most common genetic predisposition to blood clots. This means that both of child’s parents need to have factor V deficiency or owren's disease to pass it onto their child and the future offspring. Doctors can find out if your child has Factor V Leiden by genetic testing.When a result provides questionable or limited clinical utility, physicians and genetic counselors must educate patients and providers on the pros and cons of genetic testing.Our Global Patient Services team is here to help international and out-of-area families every step of the way.Access the Employee Portal for the latest COVID-19 info, policies and other employee resources. What is factor V Leiden? Factor V Leiden . Information on PatientsLikeMe.com is reported by our members and is not medical advice.

Advertising on our site helps support our mission. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. It also identifies if a patient has one or two copies of the Factor V Leiden gene. This is an autoimmune disorder in which one's own immune system attacks normal anti-clotting mechanisms.The presence of Factor V Leiden is easily diagnosed with a laboratory test. The thrombosis is usually in the venous system. The risk is higher when both copies of the gene are defective compared to Factor V Leiden carriers.
Others can be life-threatening. We do not endorse non-Cleveland Clinic products or services. Abnormal clots in the brain can also cause significant and potentially life-threatening problems.The clotting process involves many steps and substances. In the brain, they may cause swelling and prevent oxygen and nutrients from reaching delicate nervous system tissue. Factor V Leiden (FVL), or factor “5” Leiden, is a genetic mutation (change) that makes the blood more prone to abnormal clotting. This high incidence prevalence mirrors the incidence in the corresponding general populations and can be even higher in … An abnormality in the affected individual's DNA results in the production of an abnormal form of Factor V. The amount of abnormal Factor V, and the severity of disease, depends on the presence of one or two copies of the mutated gene.

Since factor V Leiden is a risk for developing blood clots in the leg or lungs, the first indication that you have the disorder may be the development of an abnormal blood clot. 9500 Euclid Avenue, Cleveland, Ohio 44195 | © 1998-2020 Mayo Foundation for Medical Education and Research (MFMER). Others can be life-threatening. Factor V Leiden Resources. The factor V Leiden mutation causes activated protein C (APC) resistance and increases the risk for venous thrombosis and pulmonary embolism.

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This video is unavailable. This can be a life-threatening situation. Factor V Leiden thrombophilia.

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